pentobarbital will decrease the extent or influence of atazanavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Mysterious.
Barbiturates can induce hepatic microsomal enzymes leading to amplified metabolism and lessened anticoagulant response of oral anticoagulants (eg, warfarin, acenocoumarol, dicumarol, and phenprocoumon); people stabilized on anticoagulant therapy may perhaps have to have dosage adjustments if barbiturates are included to or withdrawn from their dosage regimen
pentobarbital will reduce the level or influence of capivasertib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Potent or average CYP3A inducers lower capivasertib publicity, which may cut down efficacy.
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pentobarbital will minimize the extent or influence of montelukast by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.
pentobarbital will lower the extent or effect of paclitaxel protein certain by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unfamiliar.
pentobarbital will lessen the extent or effect of vincristine liposomal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.
pentobarbital will reduce the extent or effect of prednisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will lessen the extent or impact of carvedilol by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Check.
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Contraindicated (1)pentobarbital will reduce the extent or influence of lonafarnib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib is really a delicate CYP3A4 substrate. Coadministration with solid or reasonable CYP3A4 inducers is contraindicated.
pentobarbital will minimize the level or outcome of dapsone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unknown.
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